The parts of the brain that influences addiction include:
Basal ganglia. This part of the brain plays a critical role in positive forms of motivation, pleasures, and habits and routines. The areas form a central node that is often referred to as the brain's reward circuit. Drugs essentially over-stimulate this circuit generating euphoric feelings of being high. Repeated exposure makes the circuit adapt to the presence of drugs. It also diminishes its sensitivity and thus makes it hard to feel pleasure from anything besides drugs.
Extended amygdala. This part of the brain that influences stressful feelings such as unease, irritability, and anxiety. This feeling sets in once the drug fades and thus motivates the person to seek the drug again. It reaches a point where a person will use a substance to get temporary relief from the discomfort rather than get high.
Prefrontal context. This part of the brain is responsible for thinking, planning, solving problems, and exercising self-control over impulses. It is also the last part of the brain to mature, making teens more vulnerable to drug abuse. Typically a person with substance use disorder or underdeveloped prefrontal cortex will seek the drug with minimal impulse control.
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